Search results for "Health Physics and Radiation Effects"
showing 3 items of 3 documents
Hadron therapy information sharing prototype
2013
The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and rep…
Production of mass-separated Erbium-169 towards the first preclinical in vitro investigations
2021
The β−-particle-emitting erbium-169 is a potential radionuclide toward therapy of metastasized cancer diseases. It can be produced in nuclear research reactors, irradiating isotopically-enriched 168Er2O3. This path, however, is not suitable for receptor-targeted radionuclide therapy, where high specific molar activities are required. In this study, an electromagnetic isotope separation technique was applied after neutron irradiation to boost the specific activity by separating 169Er from 168Er targets. The separation efficiency increased up to 0.5% using resonant laser ionization. A subsequent chemical purification process was developed as well as activity standardization of the radionuclid…
Aging measurements with the gas electron multiplier (GEM)
2001
Abstract Continuing previous aging measurements with detectors based on the Gas Electron Multiplier (GEM), we investigated a 31×31 cm 2 triple-GEM detector, as used in the small area tracking of the COMPASS experiment at CERN. With a detector identical to those installed in the experiment, long-term high-rate exposures to 8.9 keV X-ray radiation were performed to study its aging properties. In standard operation conditions, with Ar/CO2 (70:30) gas filling and operated at an effective gain of 8.5×103, no change in gain and energy resolution is observed after collecting a total charge of 7 mC / mm 2 , corresponding to seven years of normal operation. This observation confirms previous results…